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KMID : 0941820100200010001
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Korean Journal of Clinical Pharmacy
2010 Volume.20 No. 1 p.1 ~ p.8
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Effects of Curcuma long gum preparation on the Blood Alcohol Level and Hangover
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Chu Li Ying
Nam Yun-Sung
Cho Sung-In
Yim Sung-Hyuk
Chung Zoo-Chul
Bang Joon-Seok
Son Uy-Dong
Kim Jin-Man
Koo Kyo-Hwan
Jeong Ji-Hoon
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Abstract
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We conducted a single blind, randomized and crossover clinical trial in order to test the effect of curcuma longa herbal mixture on blood alcohol level and alcohol hangover in 19 healthy volunteers. The herbal mixture did not show a statistical significance in Cmax, Tmax and AUC in alcohol disposition. The herbal mixture did not also ameliorate blood laboratory result after alcohol consumption. In contrast, the herbal mixture is shown effective on alcohol hangover. In behavior tests, the fewer subjects in the herbal mixture group were impaired with alcohol than in reference group. Moreover, the symptom severity score in the herbal mixture was lower than that in reference group. The symptom severity score was statistically especially in stomach pain, diarrhea, concentration disorder, memory and bad breath at drinking day and one day after drinking. These results indicate that the general symptoms seemed to be recovered as time goes on. From these results, it was suggested that the herbal mixture have a beneficial effect on modulating alcohol hangover.
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KEYWORD
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alcohol hangover, herbal mixture, curcuma longa, gum
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